Chronic fatigue syndrome (CFS) is a complicated condition characterised by profound fatigue that persists or relapses over six months or more.
Overview
What is Chronic Fatigue Syndrome?
Symptoms
What are the signs of Chronic Fatigue Syndrome?
Accompanied by a number of symptoms including headache, joint pain, gastrointestinal disturbance, cognitive dysfunction, visual disturbance and paraethesias (tingling, prickling or burning sensations)
Low-grade fever and chills
Sore throat
Lymphadenopathy
Myalgias and arthralgias
Sleep disturbances
Decreased ability to concentrate or remember
Allergies
General muscle weakness
Sudden onset of severe fatigue, developing over a few hours to a few days and often after an acute viral illness and persists for at least six months
Causes
What are the causes of Chronic Fatigue Syndrome?
A specific cause of CFS is not clear, but several factors may contribute to developing with CFS including:
Viruses such as human herpesvirus-6 (HHV-6) and Epstein-Barr virus (EBV)
Oxidative stress
Excessive inflammation
Mitochondrial dysfunction
Autoimmunity
Hormonal imbalance
Diagnosis
How do I know if I have Chronic Fatigue Syndrome?
There is no specific diagnostic test for CFS. A diagnosis of CFS first requires that other potential causes of fatigue be ruled out. Your doctor is likely to ask you about your medical and family history assess the diagnostic criteria for CFS including: chronic, unexplained fatigue for at least six months, which is of new onset, is not the result of ongoing exertion, is not substantially relieved by rest, and hinders occupational, social, or personal activities. Additional tests that may assist the process include:
Stress hormone profile